Atypical Callosal Morphology in Children with Speech Sound Disorder

E Luders; F Kurth; L Pigdon; G Conti-Ramsden; S Reilly; AT Morgan

Journal article

Atypical Callosal Morphology in Children with Speech Sound Disorder

E Luders, F Kurth, L Pigdon, G Conti-Ramsden, S Reilly, AT Morgan

Neuroscience | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2017

DOI: 10.1016/j.neuroscience.2017.10.039

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Abstract

Speech sound disorder (SSD) is common, yet its neurobiology is poorly understood. Recent studies indicate atypical structural and functional anomalies either in one hemisphere or both hemispheres, which might be accompanied by alterations in inter-hemispheric connectivity. Indeed, abnormalities of the corpus callosum – the main fiber tract connecting the two hemispheres – have been linked to speech and language deficits in associated disorders, such as stuttering, dyslexia, aphasia, etc. However, there is a dearth of studies examining the corpus callosum in SSD. Here, we investigated whether a sample of 18 children with SSD differed in callosal morphology from 18 typically developing childre..

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University of Melbourne Researchers

Sheena Reilly Author

Angela Morgan Author

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Awarded by National Institutes of Health

Funding Acknowledgements

EL is funded by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health (R01HD081720) and further supported by the Cousins Center for Psychoneuroimmunology at the University of California, Los Angeles (UCLA). AM is supported by National Health and Medical Research Council Practitioner Fellowship #1105008; NHMRC Centre of Research Excellence (CRE) in Child Language #1023493; NHMRC CRE in Speech and Language Neurobiology #1116976; NHMRC Project grant #1127144; NHMRC CRE Moving Ahead #1023043; and HEARing Collaborative Research Centre. This work is also supported by the Victorian Government's Operational Infrastructure Support Programme.